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Stem cells are unique cells with the ability to self-renew and, under appropriate conditions, develop into more specialized types of cells. These characteristics have made them an important area of research in regenerative medicine.

Different types of stem cells and cell-based products are regulated differently, and their safety, effectiveness, and appropriate use depend on the specific product and medical application.

While PRP/PRF are cellular fragments used in regenerative medicine, other cellular techniques have been used to restore or improve function and reduce symptoms associated with degeneration.

Adipose Derived Stem Cells (ADSC), Stromal Vascular Fraction (SVF), and Nano fat have all been investigated in the treatment of conditions such as degenerative joint disease.

Nano Fat

Nano fat is obtained through a standard liposuction procedure and the fat is processed in such a way that the mature fat cells are disrupted and tiny cells such as stem cells and vascular stromal cells, as well as various growth factors remain intact.

Lipogems®

For a nano fat procedure, the best example is the FDA cleared Lipogems® system, which has been used in over 50,000 orthopedic procedures. There are numerous other systems that work in a similar fashion. While this is not called a stem cell procedure, clinical studies have shown that it is the stem cells and other growth factors that account for the success of the procedure.

SVF

SVF is a very common type of stem cell procedure which involves obtaining fat through liposuction and separating the stromal vascular fraction (SVF) which is rich in mesenchymal stem cells.

Wharton's Jelly

Wharton’s Jelly is a birth product from donated placentas. This may commonly be referred to as umbilical stem cells, but it really is a tissue product that is rich in stem cells but also has other factors. There is extensive literature on the use of this tissue in regenerative medicine.

Exosomes

Exosomes are obtained from birth products and are commonly confused with stem cells. The idea is that the exosomes carry the important messaging signals from mesenchymal stem cells. The clinical data on exosomes to treat degenerative arthritis is generally lacking at this time.

Bone Marrow

Bone marrow derived stem cells are harvested generally from the hip bone and have been used in regenerative medicine as well. While bone marrow derived stem cells may work similar to fat derived tissue we choose not to use it because other options are more comfortable and we have extensive experience with obtaining fat.